LIPOPROTEIN (A) IN PATIENTS WITH PREMATUREMYOCARDIAL INFARCTION

Background: increased levels of lipoprotein (lp)(a) is a risk factor for coronary heart disease.in this study we evaluated levels of lp(a) in patient with acute myocardial infarction (ami)aged less than 50 years old in comparison to controls.methods: in this case-control study, we compared 98 patients with ami (case group) and anequal number of age- and sex-matched healthy subjects (control group). serum lp(a) level wasmeasured after 12 hours of fasting in both groups.results: the mean age of the case and control groups was not significantly different (45.28±5.09 vs. 44.89± 5.22 years, respectively p = 0.52).the mean lp(a) level was significantly higherin the case group than in the control group (32.5± 24.5 vs.25.2± 22.6 mg/dl, respectively p =0.04). prevalence of lp(a) . 30 mg/l was significantly higher in case group than in controlgroup (43.5% vs. 27. %, respectively, p = 0.016, or = 3.22, 95% ci = 1.24-8.3).conclusion: because of high prevalence of high lp(a) in premature ami, it is necessary tocontrol this disorder in young adults for preventing delayed mi.