ASSESSMENT OF RELATION BETWEEN MICROALBUMINURIA AND ISCHEMIC ELECTROCARDIOGRAM IN IRANIAN GENERAL POPULATION

Background: enhancement of albumin exertion in urine increases the risk of renal andischemic heart diseases (ihd). we assessed the association of urine albumin and sub-clinicalihd in a random sample of iranian general population.methods: the random sample in general population in isfahan county was recruited to thecross-sectional study. from the all sample blood pressure and lipid profile were assessed andmorning urine spot was measured for albumin and creatinine. microalbuminuria was definedeither albumin-creatinine ratio (acr) was 30-300mg. also, the standard 12 lead electrocardiogram(ecg) was carried out for all participants. the ecg pattern was divided to two categories;normal or ecg with ischemia. the logistic regression model was determined the odds ofalbuminuria for ischemic changes in ecg.results: 999 subjects, age 35-70 years, participated to study. from all, 40.8% were male. microalbuminuriawas detected in 8% and sub-clinical ecg ischemic changes were found in23.4%. the most frequent ischemic change was t wave inversion. the mean urine albumin levelsin subjects with normal ecg was 9.6±14.6 mg/ml and in ischemic group was 8.5±12.2mg/ml and they did not have statistically different. the odds ratios of neither albumin-creatinine ratio nor microalbuminuria were in significant range for risk to ischemic changes inecg of apparently healthy participants. they was consecutively or=0.9 (0.51-1.6), or=0.99(0.98-1.004).conclusion: our finding didn’t declare any association between acr and ihd. because ofshowing this association in the other study; it needs more exploration regarding to associationbetween microalbuminuria and cardiovascular diseases incidence