Synthesis and characterization of some New antimicrobial transition Metal complexes with 1,2,4-Traizole-3-thione schiff bases

Co(ii),ni(ii),cu(ii) and cd(ii) complexes of bidentate schiff bases derived from the condensation of 4-amino-5-benzyl-4h-1,2,4-triazoles-3-thione with pyridine-2-carboxyaldehyde,pyridine-3-carboxya- ldehyde and pyridine-4-carboxyaldehyde were synthesized. the schiff bases and their metal complexes were characterized by elemental and thermogravimetric analyses,spectral measurements (ft-ir,uv-vis),molar conductance and magnetic moment measurements. square planar (cu(ii) complexes),tetrahedral (cd(ii) complexes) and octahedral (co(ii) and ni(ii) complexes) geometries have been proposed. the presence of coordinated water in the metal complexes is confirmed by thermal analysis and ir data. the schiff bases act as bidentate ligands coordinating via the azomethine nitrogen and thiolate sulfur atoms. the schiff bases and their metal complexes have been screened for antimicrobial activity against six bacteria,namely staphylococcus aureus,pseudomonas aeruginosa,bacillus cereus,micrococcus luteus,escherichia coli and serratia marcescens and six fungi,namely candida albicans,geotrichum candidum,fusarium oxysporum,scopulariopsis brevicaulis,aspergillus flavus,and trichophyton rubrum.