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Natural dienoic acid derivative from the endophytic fungus DH-SO21-2012
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نویسنده
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damour h. ,hakiki a. ,proksch p. ,mosaddak m. ,fouad m.a. ,debbab a.
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منبع
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journal of materials and environmental science - 2015 - دوره : 6 - شماره : 6 - صفحه:1624 -1628
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چکیده
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Chemical investigation of the ethyl acetate extract of the fungal strain dh-so21-2012,which was isolated from healthy leaf tissues of the moroccan medicinal plant salvia officinalis,yielded a new secondary metabolite 2 together with its known congener 1 as well as the known compound 3. the structures of all compoundswere determined on the basis of 1d and 2d nmr analyses as well as mass spectrometry. the isolated compounds were subjected to various bioassays to examine their ability to inhibit the chaperone hsp90 machinery,antimicrobial and cytotoxic activities.
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کلیدواژه
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Biological activities; Fungalendophyte; Salvia officinalis
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آدرس
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institute for pharmaceutical biology and biotechnology,heinrich-heine university, Germany, laboratoire des substances naturelles et thermolyse eclaire,département de chimie,université mohamed v, Morocco, institute for pharmaceutical biology and biotechnology,heinrich-heine university, Germany, laboratoire des substances naturelles et thermolyse eclaire,département de chimie,université mohamed v, Morocco, department of pharmacognosy,faculty of pharmacy,minia university, Egypt, institute for pharmaceutical biology and biotechnology,heinrich-heine university, Germany
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Authors
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