New 1,3,4-thiadiazolines hemisynthesized from Moroccan endemic plants: Euphorbia officinarum latex

Heterocycles are inextricably woven into the life processes. the vital interest of the pharmaceutical and agrochemical industries in heterocycles is often connected with their natural occurrence. the synthesis of novel heterocyclic derivatives and investigation of their chemical and biological behaviour have gained more importance in recent decades. heterocyclic chemistry is an integral part of the chemical sciences and constitutes a considerable part of the modern researches that are occurring presently throughout the world. hemisynthesis of 1,3,4-thiadiazolic triterpenes resulting from euphorbia officinarum latex require initially preparation of their precursors,the thiosemicarbazones and gave thiadiazolic compounds characterized by new spiro carbons.