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Metal ions as antitumor complexes-review
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نویسنده
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warad i. ,eftaiha a.f. ,al-nuri m.a. ,husein a.i. ,assal m. ,abu-obaid a. ,al-zaqri n. ,hadda t.b. ,hammouti b.
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منبع
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journal of materials and environmental science - 2013 - دوره : 4 - شماره : 4 - صفحه:542 -557
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چکیده
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Metal ions are required for many critical functions in humans. scarcity of some metal ions can lead to disease. well-known examples include pernicious anemia resulting from iron deficiency,growth retardation arising from insufficient di- etary zinc,and heart disease in infants owing to copper deficiency. the ability to recognize,to understand at the molecular level,and to treat diseases caused by inadequate metal-ion function constitutes an important aspect of medicinal bioinorganic chemistry. understanding the biochemistry and molecular biology of natural detoxification mechanisms of metals can help in designing and applying chelating agents to treat metals to be excellent antitumor agents forseveral cancer types.
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کلیدواژه
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Anti-tumor; Metal ions; Polydentate ligands
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آدرس
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department of chemistry,science college,an-najah national university,p. o. box 7, Palestine, department of chemistry,science college,king saud university,p. o. box 2455, Saudi Arabia, department of chemistry,science college,an-najah national university,p. o. box 7, Palestine, department of chemistry,science college,an-najah national university,p. o. box 7, Palestine, department of chemistry,science college,king saud university,p. o. box 2455, Saudi Arabia, department of chemistry,science college,an-najah national university,p. o. box 7, Palestine, department of chemistry,science college,king saud university,p. o. box 2455, Saudi Arabia, lab of chemical material,fso,university mohammed 1er, Morocco, lcae-urac18,faculty of science,university mohammed ier, Morocco
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Authors
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