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Volatile Constituents and Cytotoxic Activity of the Fruits of Pleiogynium timorense (Dc.) Leenh
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نویسنده
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said a. ,omer e.a. ,el gendy m. a. m. ,fawzy g. ,abd el-kader a. e. ,fouad r.
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منبع
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journal of materials and environmental science - 2018 - دوره : 9 - شماره : 8 - صفحه:2274 -2279
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چکیده
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The volatile constituents which obtained from fresh fruits of pleiogynium timorense(dc.) leenh (anacardiaceae) by hydro-distillation method were investigated by gas chromatography and gas chromatography–mass spectrometry. twenty seven compounds were identified representing 98.6% of the total oils. d-limonene was the major oil constituent (64.51 %), followed by γ-terpinene (5.60%), while, α-copaene and trans- caryophyllene showed the same percentage (4.74 %). in addition, phytochemical screening, proximate analysis, total phenolic and total flavonoid contents of the fruits were determined. furthermore, the volatile constituents showed a cytotoxic effect against breast adenocarcinoma mcf7 and laryngeal carcinoma hep2 human tumor cell lines and a moderate cytotoxic effect on human hepatoma hepg2 cells.
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کلیدواژه
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Pleiogynium timorense; D-Limonene; Cytotoxic; Gambozia; volatile constituents; Anacardiaceae
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آدرس
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national research centre, department of pharmacognosy, Egypt, national research centre, medicinal and aromatic plants research department, Egypt, national research centre, department of pharmacognosy, Egypt. university of alberta, faculty of medicine and denistry, department of oncology, Canada, national research centre, department of pharmacognosy, Egypt, national research centre, department of chemical engineering, pilot laboratory, Egypt, national research centre, medicinal and aromatic plants research department, Egypt
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Authors
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