Using 1H NMR parameters for the configurational and conformational study of the 3,4-dihydro-2H-pyrrol-2-alkyl carboxylates and that of their acyclic and cyclic precursors diesters

In this article, we will present a stereochemical study of 3 types of compounds: the acyclic diesters derived from the diethyl acetamidomalonate 1, the cyclic diesters derived from the diethyl of 3.4-dihydro-5-phényl-2h-pyrrole-2.2- dicarboxylate 2, the methyl esters derived from 3.4-dihydro-2h-pyrrole-2-carboxylate 3. these compounds were prepared during our work and engaged in dipolar-1.3 cycloaddition on different symmetric dipolarophiles [1, 2]. in order to characterize and confirm the stereochemistry of these molecules, we used the 1h nmr parameters and dreiding models.