In vitro evaluation of the antioxidant and antimicrobial effects of Globularia alypum L. extracts

In the present study,extracts obtained from different parts of globularia alypum are subjected to a phytochemical screening and investigated for their antioxidant and antimicrobial activities. the results revealed the presence of saponins,polyphenols,flavonoids,tannins,terpenoids,coumarins,and cardiac glycosides. furthermore,quantitative assays showed that methanolic extract of roots was the richest in phenolic compounds with an amount of 131.48 μg equivalent of gallic acid/mg of extract. while,the methanolic extract of stems was the richest in flavonoids with an amount of 39.14 μg equivalent of quercetin/mg of extract. moreover,the antioxidant activity assessed by radical scavenging assay showed that roots extracts exhibited strong antioxidant activity. a linear relationship has been found between the total phenolic content and the antioxidant activity of the studied extracts. in addition,all plant extracts were active against gram-positive bacteria,notably those of roots which were the most efficient against bacillus subtilis and staphylococcus aureus.