Economical production of poly-3-hydroxybutyrate by bacillus cereusunder submerged and solid state fermentation

High cost of poly-3-hydroxybutyrate production remained a major hindrance for its wide range applications. in the current study poly-3-hydroxybutyrate producing bacteria were isolated from environmental sources. highest poly-3-hydroxybutyrate producing isolate bacillus cereus ps 10 was investigated for its ability to use wide range of low-cost carbon sources including agro-industrial residues,viz. wood waste,potato peel powder,saw dust,maize bran,rice husk,molasses,whey etc. for poly-3-hydroxybutyrate production under submerged fermentation.b.cereus ps 10 exhibited remarkable metabolic capability and utilized most of the crude materials as carbon source for growth and poly-3-hydroxybutyrate production. maximum poly-3-hydroxybutyrate yield was observed when glycerol (8.9 ±0.3g/l) and molasses (8.6 ±0.25 g/l) were used as carbon sources.execution of solid-state fermentation (ssf) using malt as ssf substrate showed that b. cereus ps 10 grew successfully under ssf and produced appreciable poly-3-hydroxybutyrate yield (14.4 mg/g). ability of b. cereus ps 10to utilize vast range of crude carbon sources for growth and poly-3-hydroxybutyrate production,and its capacity to grow and produce substantial poly-3-hydroxybutyrate yield under ssf reflects its potential connotation for industrial biotechnology.