Synthesis of Pyrano [2,3,d] Pyrimidines under green chemistry

Pyrano [2,3,d] pyrimidines derivatives are very important and valuable compounds in the fields of medicine,biological and pharmaceutical. in this context,we study effects and benefits of various green synthetic strategies in the synthesis of pyrano [2,3,d] pyrimidines derivatives. green chemistry is design,advancement and use of chemical products and systems that minimize or remove the utilization and formation of destructive and toxic materials. it is a universal method that is feasible to all areas of science chemistry. all synthetic processes involve the use of various substances. unfortunately majority of the chemical reagents and substances are applied in industry and chemistry laboratories are hazardous and toxic compounds which led to environmental damage,through pollution,threats to human health and resource evacuation,we need to develop and utilize more environmentally friendly protocols. therefore,all prevalent and old approaches clearly give detrimental impacts to the mankind and all living beings. green strategies open up multitudinous possibilities for performing rapid organic reactions and functional group transformations more effectively. it is quite obvious from the growing number of emerging publications in this area that the possibility to utilize green chemistry technology allows reaction conditions to be accessed that are very important and valuable for organic synthesis. in this review,we study effects and benefits of various green synthetic strategies in the synthesis of pyrano[2,3,d]pyrimidines derivatives. due to unique benefits of green reactions,new green protocols are being discovered for eco-friendly synthesis of large number of organic,pharmaceutical and natural compounds. as a result,green synthetic reactions are observing a fresh spring. © 2017,university of mohammed premier oujda morocco.