Sensitivity Pattern of Bacteria Isolated from Contact Lens Wearers in the Faculty of Pharmacy, Karachi University Student Population

Contact lens wearers are at great risk of developing microbial keratitis because of incorrectusages and unhygienic maintenance ofcontact lenses. therefore, the present study was plannedto provide data that will be helpful in selecting the anti-microbial to cure microbial keratitis.one hundred bacterial isolates from conjunctiva of contact lenses wearer were isolated,identified and subjected to in vitro antibiotic sensitivity. in vitro sensitivity testing was done bykirby-bauer disc diffusion method. out of forty-one isolates of staphylococcus epidermidisisolated in this study, 82.9% and 75.6% isolates were sensitive to amoxycillin and cephradinerespectively, where as isolates sensitive to neomycin, ciprofloxacin and chloramphenicolwere found to be 95%, 92.9% and 87.8%, respectively. thirty-nine isolates of pseudomonasaeruginosa showed sensitivity to amoxicillin (2.6%), cephradine (7.7%), neomycin (69.2%),ciprofloxacin (82%), imipenem (84.4%) and chloramphenicol (28.3%), respectively. multiresistantstrains of pathogenic, as well as opportunistic microorganisms were isolated duringthe study. the results show a need for continuous monitoring of bacterial resistance trends.