Antimicrobial Activity of Indigenous Strains of Aureobasidium Isolated From Santalum Album Leaves

Although more than 3000 antibiotics have been reported from actinomycetesl higherfungi; biotechnological potential of yeasts and yeast-like fungi with respect to productionof antimicrobial compounds has not been sufficiently investigated. we examined theantimicrobial activity of 11 strains of aureobasidium pullulans (two new isolates and ninestandard strains). all the strains of aureobasidium pullulans inhibited ps. jluorescen s, butnone of these strains could inhibit candida albicans and s. cerevisiae. interestingly, theyeast pichia angusta was inhibited by six of the a. pullulans strains used in the presentinvestigation. two indigenous isolates of aureobasidium natural isolate 1 (n!. 1) andnatural isolate 2 (n!. 2) showed antibacterial activity against the gram-negative cultures;most of which were resistant to gentamicin. this study provides evidence that a. pullulansis a promising producer of antimicrobial agents for better chemotherapeutic agents, possiblyagainst pseudomonals infections.