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Antioxidant, Antibacterial Activities and General Toxicity of Alnus glutinosa, Fraxinus excelsior and Papaver rhoeas
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نویسنده
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Middleton Patricia ,Stewart Fiona ,Al-Qahtani Salem ,Egan Paula ,O'Rourke Ciara ,Abdulrahman Aysha ,Byres Maureen ,Middleton Moira ,Kumarasamy Yashodharan ,Shoeb Mohammad ,Nahar Lutfun ,Delazar Abbas ,Dey Sarker Satyajit
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منبع
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iranian journal of pharmaceutical research - 2005 - دوره : 4 - شماره : 2 - صفحه:81 -86
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چکیده
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Alnus glut i nosa, fraxinus excelsior and papaver rhoeas have long been used in folkloricmedicine for the treatment of various ailments. as part of our continuing screening of plantextracts for biological activities, the extracts of a. glu tinosa, f excelsior and p rhoeashave been screened for their antioxidant and antibac terial activit ies, as well as their generaltoxicity towards brine shrimps. among the extracts, the methanol (meoh) extract of fexcelsior displayed the highest level of antioxidant activity (rc50= 1.35x 10-2 rng/ml.) and thedichloromethane (dcm) extract of p rhoeas was the most toxic extract towards brine shrimps(ld50=2.4x10-2 mg/ml.). the n-hexane and dcm extracts of f excelsior and the meohextract of a. glutinosa were active (mic values were within 1.25x i0-1 and 1.00 mg/ml)against al l 8 bacterial species tested, including methicillin-resistant staphylo coccus aureus(mrsa).
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کلیدواژه
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Alnus glutinosa; Fraxinus excelsior; Papavar rhoeas; 2. 2-Diphenyl-lpicrylhydrazyl(DPPH) ; Antibacterial; Brine shrimp lethality assay.
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آدرس
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The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Pharmacy, UK, The Robert Gordon University, School of Life Sciences, UK, tabriz university of medical sciences, School of Pharmacy, ایران, University 0f Ulster, School of Biomedical Sciences, UK
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پست الکترونیکی
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s.sarker@ul ster.ac.uk
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Authors
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