|
|
|
|
review on approved and inprogress covid-19 vaccines
|
|
|
|
|
|
|
|
نویسنده
|
farnudiyan-habibi amir ,mirjani mobina ,montazeri vahideh ,aliebrahimi shima ,katouzian iman ,abdolhosseini saeed ,rahmani ali ,keyvani hossein ,ostad nasser ,rad-malekshahi mazda ,farnudiyan-habibi amir ,mirjani mobina ,montazeri vahideh ,aliebrahimi shima ,katouzian iman ,abdolhosseini saeed ,rahmani ali ,keyvani hossein ,ostad nasser ,rad-malekshahi mazda
|
|
منبع
|
iranian journal of pharmaceutical research - 2022 - دوره : 21 - شماره : 1 - صفحه:1 -19
|
|
چکیده
|
The last generation of coronavirus named covid-19 is responsible for the recent worldwide outbreak. concerning the widespread and quick predominance, there is a critical requirement for designing appropriate vaccines to surmount this grave problem. correspondingly, in this revision, covid-19 vaccines (which are being developed until march 29th, 2021) are classified into specific and non-specific categories. specific vaccines comprise genetic-based vaccines (mrna, dna), vector-based, protein/recombinant protein vaccines, inactivated viruses, live-attenuated vaccines, and novel strategies including microneedle arrays (mnas), and nanoparticles vaccines. moreover, specific vaccines such as bcg, mrr, and a few other vaccines are considered nonspecific. what is more, according to the significance of bioinformatic sciences in the cuttingedge vaccine design and rapid outbreak of covid-19, herein, bioinformatic principles including reverse vaccinology, epitopes prediction/selection and, their further applications in the design of vaccines are discussed. last but not least, safety, challenges, advantages, and future prospects of covid-19 vaccines are highlighted.
|
|
کلیدواژه
|
covid-19 ,reverse vaccinology ,bioinformatic ,epitope prediction ,mrna vaccine
|
|
آدرس
|
tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran. tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran, tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran. tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran, virtual university of medical sciences, department of clinical pharmacy, iran. virtual university of medical sciences, department of clinical pharmacy, iran, virtualuniversity of medical sciences, department of medical education, iran. virtualuniversity of medical sciences, department of medical education, iran, monash university, australasian nanoscience and nanotechnology initiative (anni), australia. monash university, australasian nanoscience and nanotechnology initiative (anni), australia, university of tehran, school ofelectrical and computer engineering, college of engineering, iran. university of tehran, school ofelectrical and computer engineering, college of engineering, iran, tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran. tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran, iran university of medical sciences, school of medicine, department of virology, iran. iran university of medical sciences, school of medicine, department of virology, iran, tehran university of medical sciences, toxicology and poisoning research centre, faculty of pharmacy, department of toxicology and pharmacology, iran. tehran university of medical sciences, toxicology and poisoning research centre, faculty of pharmacy, department of toxicology and pharmacology, iran, tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran. tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran, tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran, tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran, virtual university of medical sciences, department of clinical pharmacy, iran, virtualuniversity of medical sciences, department of medical education, iran, monash university, australasian nanoscience and nanotechnology initiative (anni), australia, university of tehran, school ofelectrical and computer engineering, college of engineering, iran, tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran, iran university of medical sciences, school of medicine, department of virology, iran, tehran university of medical sciences, toxicology and poisoning research centre, faculty of pharmacy, department of toxicology and pharmacology, iran, tehran university ofmedical sciences, faculty of pharmacy, medical biomaterials research center, department of pharmaceutical biomaterials, iran
|
|
پست الکترونیکی
|
m-radmalekshahi@sina.tums.ac.ir
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|