autologous platelet rich fibrin versus steroid in ultrasound-guided sacroiliac joint injection for joint dysfunction: randomized comparative study

Background: sacroiliac joint (sij) discomfort is frequently treated with steroids, although the relief is often temporary. the use of platelet-rich fibrin (prf) may aid in tissue healing and prolong pain relief. objectives: this study aims to compare the analgesic effects of a single autologous prf injection with the commonly used steroid in ultrasound-guided intra-articular sij injections. methods: this randomized clinical trial was conducted in the department of anesthesiology and pain management at fayoum university hospitals. the study included 94 adult patients with sij dysfunction confirmed by positive diagnostic tests. all patients were randomly assigned into two equal groups to receive either an ultrasound-guided prf injection (group p, n = 47) or a steroid injection (group s, n = 47). results: the visual analog scale (vas) score immediately after injection in group p was 7.51 ± 0.78 (mean ± sd), while in sroup s, it was 5.91 ± 0.54, with a highly significant difference between the two groups (p < 0.001). at six months, the vas score was 3.51 ± 0.78 in group p compared to 4.68 ± 0.63 in group s, again showing a highly significant difference (p < 0.001). there was no significant difference in the oswestry disability index (odi) between the groups at one and six months. conclusions: intra-articular prf injection is an effective therapy option for sij-related low back pain, offering prolonged pain relief compared to steroid injections.