Serum Klotho Levels in Trained Athletes

Background: klotho is an anti-aging protein that is predominantly secreted by the kidneys. objectives: the aim of the study was to measure and compare the circulating klotho levels in the serum of trained athletes and in healthy, non-athlete controls. materials and methods: thirty trained football players were enrolled and their serum klotho levels were measured the morning after their last evening exercise training. results: the plasma free klotho concentration was significantly higher in the athlete group (3.375 ± 1.48 ng/ml) compared to the non-athletes (1.39 ± 0.43 ng/ml) (p < 0.05). serum levels of cholesterol, triglycerides, calcium, and phosphorus were not significantly different between the two groups. conclusions: regular aerobic exercise could increase plasma klotho levels, and this could be an explanation for exercise-related anti-aging effects.background: klotho is an anti-aging protein that is predominantly secreted by the kidneys. objectives: the aim of the study was to measure and compare the circulating klotho levels in the serum of trained athletes and in healthy, non-athlete controls. materials and methods: thirty trained football players were enrolled and their serum klotho levels were measured the morning after their last evening exercise training. results: the plasma free klotho concentration was significantly higher in the athlete group (3.375 ± 1.48 ng/ml) compared to the non-athletes (1.39 ± 0.43 ng/ml) (p < 0.05). serum levels of cholesterol, triglycerides, calcium, and phosphorus were not significantly different between the two groups. conclusions: regular aerobic exercise could increase plasma klotho levels, and this could be an explanation for exercise-related anti-aging effects.