Ubiquinol Effect on Sperm Parameters in Subfertile Men Who Have Astheno-Teratozoospermia With Normal Sperm Concentration

Background: considering all the couples willing and trying to get pregnant, the incidence of infertility is 15% of which approximately half of the cases are due to the male factors.objectives: the aim of this study was the investigation of the effects of ubiquinol, reduced form of coenzyme q10 (co-q10), an empiric treatment modality, on sperm parameters in idiopathic subfertility.patients and methods: in this retrospective study, 62 patients who had received 100 mg ubiquinol twice a day for six months due to idiopathic infertility since january 2012 to january 2013 were included. only infertile patients with astheno-teratozoospermia without any identified etiology and with a spermatozoa concentration of greater than 13 × 106/ml were included.results: the increase in mean values of concentration after the ubiquinol treatment was not statistically significant (p value = 0.065). however, the changes in morphology and motility (fast progressive [a] and a + slow progressive [b]) were statistically significant (p < 0.00).conclusions: the weakness of the literature with regard to coenzyme q10 is about its effects in patients with severely diminished sperm densities and the physiologic steps of morphologic improvements.