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Direct Renin Inhibitor: Aliskiren in Chronic Kidney Disease
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نویسنده
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Morishita Yoshiyuki ,Kusano Eiji
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منبع
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nephro-urology monthly - 2013 - دوره : 5 - شماره : 1 - صفحه:668 -672
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چکیده
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The renin-angiotensin-aldosterone system (raas) plays pivotal roles in the pathogenesis of chronic kidney disease (ckd) progression and its increased complications such as hypertension (ht) and cardiovascular diseases (cvd). previous studies suggested that aliskiren a direct renin inhibitor, blocks raas and may be effective for the management of ckd and its complications. this review focuses on the effects of aliskiren on ckd.
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کلیدواژه
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Kidney Failure ,Chronic; Renin-Angiotensin System; Aliskiren; Blood Pressure; Cardiovascular Diseases
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آدرس
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Jichi Medical University, Division of Nephrology, Department of Medicine, Japan, Jichi Medical University, Division of Nephrology, Department of Medicine, Japan
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Authors
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