Ultrapure Dialysis Fluid: A New Standard for Contemporary Hemodialysis

The concept of renal replacement therapy (rrt) has evolved considerably over the last 2 decades. dialysis, a key component of rrt intended to clear uremic toxins and periodically restore the internal milieu composition, has benefited from considerable advances in dialysis technology (bicarbonate-buffered dialysis fluid, ultrafiltration- controlled systems, profiling systems, blood volume and temperature control, direct quantification, and high-flux dialyzers) and innovative adjunctive drug therapies designed to correct anemia (erythropoietinstimulating agents (esa), iv iron, etc.), metabolic bone disease (vitamin d and analogs, calcimimetics, etc.), and associated metabolic disorders (lipid-lowering agents, antioxidants, etc.).