the effect of acei/arb on the outcomes of covid-19 hospitalized patients

Considering that there are different reports about the effects of angiotensin ii type-i receptor blockers (arb) and angiotensin-converting enzyme inhibitors (acei) on the outcomes of the patients with covid-19, we aimed to conduct this retrospective study on 138 hypertensive patients (81 acei/arb users) to assess the patients’ outcomes by comparing acei/arb and non-acei/arb users. multivariate adjusted cox regression model, by considering the effect of other variables, demonstrated that increased age (hr = 1.04, 95% ci = 1.01 -1.07, p =0.003) and non- acei/arb users (hr = 2.12 95% ci = 1.12 - 4.13, p = 0.021) were associated with increased risk of in-hospital mortality in about one week follow-up. in conclusion, we found that in-hospital mortality was lower in acei/arb users, showing the positive effect of these treatments on patients’ outcomes.