the effect of body mass index on patient and graft survival rate in kidney transplanted patients in iran

Background: the number of patients with overweight and obesity requiring renal transplant in the past 2 decades increased considerably. objectives: the current study aimed at evaluating the effect of body mass index (bmi) on graft and patients survival rate. design: in the current retrospective, cross sectional study, transplant recipients were divided into 3 groups based on their bmi: group 1 (bmi < 18.5 kg/m^2 ), group 2 (bmi = 18.5 to 25 kg/m^2 ), and group 3 (bmi > 25 kg/m^2 ). kaplan-meier formula was used to calculate the patient survival rate, log-rank test to compare the survival curves, analysis of variance (anova) to compare continuous variables, and the chi-square test to compare the classified data. statistical analysis was performed by spss version 19. p values ≤ 0.05 were considered significant. results: the 5-year follow-up on patients’ survival rate in groups 1, 2, and 3 was 91% ± 0.03%, 91% ± 0.01%, and 80 ± 0.03%, respectively. also, the 5-year graft survival rate in groups 1, 2, and 3 was 90% ± 0.02%, 85% ± 0.02%, and 76 ± 0.03%, respectively. there were significant differences between bmi status and gender of the recipients (p value = 0.003) and those of the donors (p value = 0.003), type of kidney in donors (p value = 0.001), type of dialysis in recipient (p value = 0.001), history of type 2 diabetes mellitus in recipient (p value = 0.001), recipient age (p value = 0.001), duration of hospitalization (p = 0.026), cholesterol levels after 1 year (p value = 0.001), and bmi status of the recipient. conclusions: the results also indicated that the graft survival rate of the recipients was not statistically different in terms of bmi; thus, the results suggested that to allow of counting in patients included overweight and obesity kidney transplantation as appropriate action treatment.