transarterial chemoembolization for hepatic metastasis of solitary fibrous tumor

Background: solitary fibrous tumors (sft) are rare soft tissue tumors with a typically benign clinical course; however, up to 35% of sft exhibit metastasis, resulting in a poor prognosis. the management of hepatic metastasis of sft is yet to be established because of its rarity of cases. objectives: herein, we report the clinical results of 13 transarterial chemoembolization (tace) sessions for hepatic metastasis in 5 patients with sft. patients and methods: patients with hepatic metastases from sft who underwent tace between may 2005 and april 2021 were retrospectively reviewed. tumor response was evaluated using the modified response evaluation criteria in solid tumors (mrecist). results: five patients (one male, mean age: 59.2 years) underwent 13 tace sessions, resulting in four partial responses (pr, 30.8%), four stable disease cases (30.8%), and five progressive disease cases (38.5%). no severe complications occurred. four of seven sessions (57.1%) of selective tace showed partial response (pr). the mean progression-free survival (pfs) was 2.3 months (range: 0 - 8 months), and for sessions with pr, the mean pfs was 6.3 months (range: 3 - 8 months). the mean overall survival was 32.7 months (range: 18 - 44 months). conclusion: this report suggests that tace might be a potentially safe treatment option for hepatic metastasis of sft, and it could offer a benefit in controlling local tumor growth in cases where selective tace is applicable.