mid-term outcome following pipeline embolization of unruptured intracranial aneurysms

Background: as an advanced generation of flow diverters (fd), pipeline embolization device (ped) is introduced for endovascular aneurysm occlusion. in the present study, we aimed to present the mid-term results after endovascular treatment of unruptured intracranial aneurysms using ped. patients and methods: a total of 20 patients with 20 intracranial wide neck aneurysms were treated with ped between july and october 2010. patients were followed up 4 to 8 months after the procedure. digital subtraction angiography (dsa) was carried out to assess stent integrity, displacement, and the presence of residual aneurysm. results: out of 20 participants, ped deployment was successful in 19; whereas, intervention failed in one patient due to technical factors in device deployment. no severe acute complications were observed. one patient died after three months as a result of subarachnoid hemorrhage (sah). out of the remaining patients, dsa showed complete occlusion of aneurysms in 14 individuals (77.8%), while in four patients (22.2%), residual aneurysm was noted. stent migration was not observed in any patients. intra-stent stenosis (25% - 50%) was visualized in only one patient (5.5%). conclusion: this study showed promising mid-term results for the pipeline embolization device in the treatment of unruptured intracranial aneurysms. larger studies with longer follow-up duration are warranted.