association of ischemic heart disease assessed by radionuclide myocardial perfusion imaging with bone mineral density measurements by dual-energy x-ray absorptiometry and serum vitamin d deficiency

Background: because of the increasing prevalence of both ischemic heart diseases and vitamin d deficiency and also due to recent evidences on association between these two phenomena, it is vital to clarify the association of ischemic heart disease with vitamin d deficiency and low bone mass. objectives: the aim of the present study was to assess the relationship between low serum vitamin d and low bone mass measured by dual-energy x-ray absorptiometry (dexa) with ischemic heart disease assessed by the functional radionuclide myocardial perfusion imaging (mpi). patients and methods: in this cross-sectional study, 204 consecutive patients aged older than 50 years who were candidates for mpi were included. blood sample was extracted to measure the level of serum 25-oh vitamin d using a special kit (ids kit). then, the patients were assessed by mpi. within a month of myocardial perfusion scanning, subjects underwent bone mineral density (bmd) measurements by dexa method. results: there was no significant difference in serum level of vitamin d between patients with normal and those with abnormal mpi results. in addition, no significant correlation was detected between bmd and myocardial ischemia. conclusion: coronary atherosclerosis may not be associated with the severity of low bone mass or level of vitamin d adequacy.