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The Effects of Cured Dentin Bonding Agents on Secretion of Pro-Inflammatory Cytokines, IL-1beta and TNF-ل, by Human Monocytes
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نویسنده
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Hadjati Jamshid ,Vahid Alaviye ,Ghabraei Shohre ,Kermanshah Hamid
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منبع
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iranian journal of allergy, asthma and immunology - 2008 - دوره : 7 - شماره : 3 - صفحه:177 -180
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چکیده
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Dentin bonding agents (dba) have been used as root-end filling materials. presentstudy evaluated the effects of polymerized dba on secretion of pro-inflammatory cytokinesby normal human monocytes.in this study, monocytes were directly isolated from human peripheral blood, andexposed to cured scotch bond 1 (single bond) and prime and bond for 36 and 72 hours.secretion of il-1beta and tnf-alpha in the presence of lipopolysaccaharide was evaluated insupernatants of monocyte culture.dbas significantly caused reduction of cytokine production by human monocytes after36 and 72 hours. prime and bond exposure caused more prominent decrease in tnf-alphaproduction after 72 hours.we conclude that dba in polymerized form can alter normal function of humanmonocytes.
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کلیدواژه
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Dentin bonding agents; IL-1Beta ; Monocytes; TNF-alpha
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آدرس
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tehran university of medical sciences tums, School of Medicine, Department of Immunology, ایران, tehran university of medical sciences tums, School of Dentistry, Department of Endodontics, ایران, tehran university of medical sciences tums, School of Dentistry, Department of Endodontics, ایران, tehran university of medical sciences tums, School of Dentistry, ایران
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پست الکترونیکی
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hajatij@sina.tums.ac.ir
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Authors
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