Intraoperative Anaphylactic Shock in a Child with No History of Type I Hypersensitivity

Natural rubber latex is the second most implicated agent in intraoperative anaphylacticreactions.this report describes a case of intraoperative anaphylaxis occurring in a non-atopicfourteen-year-old girl undergoing multiple surgical procedures, but without spina bifida, inwhich latex surgical gloves were the main culprit for the anaphylactic reactions. clinicalmanifestations of an anaphylactic reaction were also experienced during the examination ofthe possible cause of intraoperative anaphylaxis by skin prick testing with a latex allergenextract. skin tests with anesthetics were negative. specific ige to latex was positive at 92.9kua/l (class 5). the molecular basis for the reported intraoperative anaphylaxis wasascribed to three low-molecular mass latex allergens (10-15 kd) detected in the brand oflatex surgical gloves used during the operation.given the potential of a dramatic outcome, latex allergy testing as a regular preoperativemeasure may contribute to the reduction of anaphylactic reactions during surgicalinterventions.