Associated markers for adult-onset allergic asthma

The clinical behavior of asthma varies with age at onset. this study was undertaken to identify associated markers of adult-onset allergic asthma (age ≥20 years). this cross-sectional study compared two groups: 58 patients with asthma onset at <20 years and 66 with onset at ≥20 years. they were compared depending on results of clinical history,and body mass index (bmi),aeroallergen sensitization,total serum ige,eosinophil count,asthma control test,and asthma severity level. ages at first asthma episode were 10.0 ± 6.6 and 33.4 ± 10.5 (p <0.001) in the <20 and ≥20 group,respectively. bmi was higher in adult asthmatic subjects (29.8 versus 27.1,p= 0.017),but bmi ≥30 kg/m2 was not associated with asthma onset in ≥20 years (odds ratio [or] = 1.56,95% confidence interval [ci] 0.759 to 3.211; p= 0.227). after multivariate analysis,allergic rhinitis and ige ≥150 iu/ml were negatively correlated with asthma onset in ≥20 years old (or adjusted [ora] = 0.255,95% ci 0.078 to 0.837,p= 0.024,and ora = 0.385,95% ci 0.175 to 0.849,p= 0.018,respectively). adult-onset allergic asthma was not different from early-onset asthma. copyright © autumn 2015,iran j allergy asthma immunol. all rights reserved.