Rescue potency of Eucalyptus oil against gamma-rays induced gastric ulceration

Background: eucalyptus oil often used for medicinal purposes. aims: the eucalyptus oil gastro protective impact investigated against gamma-rays-exposure-induced gastric ulceration in rats. materials and methods: thirty-two rats were divided equally into 4groups; control, eucalyptus oil (100mg/ kg), gamma-rays (7gy) and eucalyptus oil plus gamma-rays treated groups. the stomach histopathology samples were examined. the levels of malondialdehyde, reduced glutathione, superoxide dismutase, tumour necrosis factor-α and the interleukin-1β were assessed. results: the stomach histopathological examination revealed that pre-treatment with eucalyptus oil enhanced regeneration of mucosal crypt cells. the results revealed a decreased level of stomach malondialdehyde, inflammatory markers, increased levels of stomach antioxidants markers in eucalyptus oil plus gamma-rays treated group. conclusion: eucalyptus oil ameliorates gamma-rays-induced gastric ulceration that could attribute to its antioxidant, anti-apoptotic and radioprotective activities.