CT-Value (HU and CT-Value ratioin) differentialdiagnosis of small hepatocellular carcinoma fromfocal nodular hyperplasia

Background: the objective was to explore the value of the ct valuedifference (△hu) and ct value ratio (cvr) between the hepatic arterial (ap),portal (pp), and delayed phases (dp) to differentiate the small hepatocellularcarcinoma (shcc, ≤ 3 cm) from the small focal nodular hyperplasia (sfnh, ≤ 3cm). materials and methods: all the lesions were confirmed by clinically and/or pathologically and all the patients underwent triple-phase enhanced ctscans. the lesions’ ct values (lcv) and the surrounding normal liverparenchyma (ncv) of the enhancement phases were measured separately,the △hu and cvr were calculated. results: the median age and the male/female ratios of the shcc and sfnh have statistically significant, and the sizehaven’t statistically significant. the △hu and cvr of the ap, pp, and dp of theshccs and sfnhs were statistically significant, respectively. the area undercurve of △hu and cvr of ap, pp and dp were increased gradually. when the△hu and cvr of the ap, pp and dp were 105.800hu vs. 1.516, -12.600hu vs.0.949, -19.750 hu vs. 0.951, obtained the maximum you-den indexes. thecorresponding sensitivity and specificity were 80.6 % and 90.1 % vs. 88.90%and 72.1%, 100% and 81.1% vs. 100% and 81.1%, 94.4 % and 96.4% vs. 94.4 %and 96.4%, respectively. conclusion: the shcc was highly suggested when△hu and cvr are no greater than 105.800hu and 1.516, -12.600hu and0.949, -19.750 hu and 0.951 of the ap, pp, and dp in the middle-aged andelderly male patients, especially in the dp.