Protective role of ferulic acid against the damaging effect induced by electromagnetic waves on rat liver and intestine tissues

Background: the increasing use of mobile phones in daily life causes manyconcerns about their effects on human health. therefore, this work was designed tostudy the effects of exposure to 1800 mhz electromagnetic waves (emw) on theliver and intestine of male albino rats and the protective role of ferulic acid (fa)against these harmful effects. materials and methods: twenty-four male albinorats were randomly divided into four groups as follows: 1) control group, 2) treatedgroup given fa, 3) irradiated group exposed to 1800 mhz emw and 4) treatedirradiatedgroup given fa then exposed to emw. biochemical analysis andhistopathological examination were performed. results: a significant increase inserum activities of alanine transaminase and aspartate transaminase, andserum levels of interleukin (il)-6 and tumor necrosis factor-α was shown inthe irradiated group, while il-10 was significantly decreased. there was asignificant decrease in lactate dehydrogenase and total antioxidant capacityin the tissues of liver and intestine of this group as well as somehistopathological changes. all these serum and tissues parameters andhistopathological changes were improved in the group treated with fa beforeexposure to emw. conclusion: prolonged exposure to emw emitted from mobilephones might produce harmful effects in the liver and intestinal tissues of albinorats. these effects can be prevented by fa administration which may be protectiveagainst tissue damage induced by emw through the suppression of oxidative stress.