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   Toxicological Investigation of Acute Carbon Monoxide Poisoning in ‎Four Occupants of a Fuming Sport Utility Vehicle ‎  
   
نویسنده Nnoli Martin ,Lebgbosi Nwidu Lucky ,Chukwuonye Innocent Ijezie ,Nwabuko Collins Ogbonna
منبع iranian journal of toxicology - 2014 - دوره : 7 - شماره : 23 - صفحه:973 -976
چکیده    Background: this toxicological investigation involves a report on the death of four ‎occupants of a sport utility vehicle on one of the major busy federal roads of nigeria ‎where they were held for up to three hours in a traffic jam while the car was steaming.‎methods: autopsy was executed using the standard procedure and toxicological ‎analysis was done using simple spectrophotometric method to establish the level of ‎carboxyhaemoglobin (hbco) in peripheral blood in the four occupants. ‎results: the autopsy report indicated generalized cyanosis, sub-conjuctival ‎hemorrhages, marked laryngo-trachea edema with severe hyperemia with frothy fluid ‎discharges characteristic of carbon monoxide poisoning. toxicological report of the level ‎of hbco in part per million (ppm) in the peripheral blood of the four occupants was a= ‎‎650 ppm; b= 500 ppm; c= 480 ppm, and d= 495 ppm against the maximum permissible ‎level of 50 ppm.‎conclusion: the sudden death of the four occupants was due to excessive inhalation ‎of the carbon monoxide gas from the exhaust fumes leaking into the cabin of the car. ‎the poor road network, numerous potholes, and traffic jam in most of roads in nigeria ‎could have exacerbated a leaky exhaust of the smoky second hand suv car leading to ‎the acute carbon monoxide poisoning. ‎
کلیدواژه Acute Poisoning ,Autopsy ,Carbon Monoxide ,Toxicological Studies
آدرس ‎ Department of Pathology and Forensic Medicine, University of Calabar, Cross-River State, Nigeria.‎, Nigeria, ‎ Department of Pharmacology/Toxicology, Wilberforce Island, Bayelsa State, Nigeria. ‎, Nigeria, Department of Internal Medicine/Hematology, Federal Medical Center Umuahia, Abia State, Nigeria.‎, Nigeria, Department of Hematology, Federal Medical Center, Umuahia, Abia State, Nigeria.‎, Nigeria
 
     
   
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