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   Antioxidant and Inhibitory Activities of Enzymes Linked To Type Ii Diabetes Mellitus: the Novel Role of Chrysobalanus Orbicularis Leaf Extract  
   
نویسنده Lisa Ekakitie ,Ojo Oluwafemi ,Oyinloye Babatunji ,Ajiboye Basiru
منبع Iranian Journal Of Toxicology - 2020 - دوره : 14 - شماره : 3 - صفحه:179 -186
چکیده    Background: chrysobalanus orbicularis is commonly used as food, the seeds as a spice for the popular pepper soup, and the leaves are traditionally utilized for managing type ii diabetes mellitus (t2dm) in the niger delta area of nigeria. due to the limited scientific evidence on c. orbicularis, this study investigated its antioxidant and inhibitory properties against major enzymes linked to t2dm. methods: the antioxidant activity was measured via methods for possible scavenging potentials. the alpha;amylase and alpha;glucosidase inhibitory activities were examined using a standard model.results: the c. orbicularis aqueous leaf extract compared well with the standard compounds, revealing the high antioxidant and inhibitory properties against alpha;amylase and alpha; glucosidase. conclusion: the findings validate the conventional application of c. orbicularis in the treatment of patients with type ii diabetes mellitus and other oxidative stressrelated disorders.
کلیدواژه Antioxidant Activity ,C. Orbicularis ,Diabetes Mellitus ,Medicinal Plants
آدرس Afe Babalola University, Biochemical Toxicology And Biotechnology Research Laboratories, Department Of Biochemistry, Nigeria, Landmark University, Department Of Biochemistry, Nigeria, Afe Babalola University, Department Of Biochemistry, Biochemical Toxicology And Biotechnology Research Laboratories, Nigeria. Biotechnology And Structural Biology (Bsb) Group, Department Of Biochemistry And Microbiology, Nigeria. University Of Zululand, Department Of Biochemistry And Microbiology, Biotechnology And Structural Biology (Bsb) Group, South Africa, Afe Babalola University, Biochemical Toxicology And Biotechnology Research Laboratories, Department Of Biochemistry, Nigeria
پست الکترونیکی bash1428@yahoo.co.uk
 
     
   
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