the effect of luteal phase gonadotropin-releasing hormone antagonist administration on ivf outcomes in women at risk of ohss

Background: gonadotropin-releasing hormone (gnrh) plays essential roles in embryo implantation, invasion of trophoblastic tissue, and steroid synthesis in the placenta. objective: the aim of this study was to evaluate the effect of gnrh antagonist administration on pregnancy outcomes in early implantation period. materials and methods: in this retrospective study, 94 infertile women undergoing gnrh antagonist protocol who were at risk of ovarian hyperstimulation syndrome (ohss) were included. sixty-seven patients (group i) received cetrorelix 0.25 mg/daily in the luteal phase for 3 days while in 27 participants (group ii), it was not administered. pregnancy outcomes were assessed based on chemical and clinical pregnancy rates. results: the pregnancy outcomes were not significantly different between two groups (p=0.224). conclusion: the present study proposed that luteal phase gnrh antagonist administration does not influence the chance of successful pregnancy outcomes.