fertility sparing surgery in gestational trophoblastic neoplasia: a report of 4 cases

Background: gestational trophoblastic neoplasia (gtn) is a curable disease thatinvolves the development of malignant tumor in the woman after a normal or molarpregnancy. the position of surgery in gtn is not properly specified and is changingdue to new chemotherapy protocols. however, the role of surgery is highlighted inchemotherapyresistant gtn. other indications of surgery in trophoblastic diseasesare drug toxicity and uterine perforation. based on the fact that most women incertain age tend to preserve fertility, this study reported 4 cases of successfultreatment after fertility sparing surgery.case: a hospitalbased casereport study was carried out to investigate the role ofsurgery in 4 patients with gtn. in this study, acute complications, such as intraabdominalbleeding and liver dysfunction due to chemotherapy occurred in somepatients. surgery was performed and all cases underwent localized tumor removalwhile preserving the uterus. no hysterectomy surgery was performed.conclusion: surgery is supposed in specific cases of gtn, who desire preservingfertility.