Triage By Cervical Length Sonographic Measurements For Targeted Therapy in Threatened Preterm Labor: A Double Blind Randomized Clinical Trial

Background: preterm labor and birth are associated with several neonatal complications including respiratory distress syndrome and intraventricular hemorrhage. differentiating true and false labor pain is a dilemma to obstetricians. objective: to elucidate the role of cervical length measurement in prediction of birth in pregnant women with threatened preterm labor. materials and methods: in this double blind randomized clinical trial, 120 women with gestational age <34 wk who presented painful uterine contractions randomly assigned to undergo measurement of cervical length. patients were registered in the hospital and a unit number was given. based on the unit numbers, patients were randomly assigned to two groups using a computerized random digit generator. all participants were managed accordingly (n=65) or to receive tocolysis as planned (n=55). tocolysis was prescribed when cervical length was <15 mm while those with cervical length ≥15 mm were managed expectantly. delivery within 7 days of the presentation was the primary outcome. results: this rct showed in case group, 78.9% of patient with cervical length <15 mm were delivered within 7 days and only 21.1% of them maintained their pregnancy. of those with cervical length ≥15 mm, only 15.2% were delivered within the study period and the rest (84.8%) maintained their pregnancy (p<0.001). conclusion: “our results indicate that in women who presented preterm labor symptoms, cervical length measurement will result in decreased unnecessary tocolytic treatment. women with cervical length ≥15 mm should not receive tocolysis, however, withholding corticosteroid therapy in these patients needs further evidence.