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   effect of nelumbo nucifera seeds on the reproductive organs of female rats  
   
نویسنده mutreja anju ,agarwal meera ,kushwaha sonalika ,chauhan alka
منبع international journal of reproductive biomedicine - 2008 - دوره : 6 - شماره : 1 - صفحه:7 -11
چکیده    Background: nelumbo nucifera has been used as antifertility agent in females by thelocal tribals of rajasthan especially of udaipur district india.objective: the present study was conducted to investigate the effect of nelumbonucifera on the fertility and general physiology in female rats.materials and methods: 20 female albino rats were taken and divided into two groups.group 1 served as control and group 2 received ethanolic extract at dose of 800mg/kgb.wt. for investigating the nature of the drug and antifertility effect. vaginal smear wasmonitored everyday in the morning to study the estrous cycle. on day 41st all theanimals were sacrificed and various haematological and biochemical parameters wereestimated.results: data revealed that oral administration of nelumbo nucifera extract broughtabout a significant decline in the weight of ovary; control (43±4.75mg), nelumboextract treated (25±3.86mg), uterus; control (236±0.004mg), nelumbo extract treated(214±0.007mg) and vagina; control (221±0.002mg), nelumbo extract treated(178±0.003mg) as well as protein and glycogen level, however cholesterol levelincreased significantly. in addition, the diestrous phase of the estrous cycle was found tobe prolonged; control (1.81±0.21) days, nelumbo extract treated (3.62±0.42) days.conclusion: these results suggest that nelumbo nucifera has the anti-estrogenic naturewithout altering the general physiology of the female rats.
کلیدواژه anti-estrogenic ,female rats ,nelumbo nucifera ,estrous cycle
آدرس reproductive physiology and biochemistry section, center for advanced studies, department of zoology, university of rajasthan, jaipur, india., India, reproductive physiology and biochemistry section, center for advanced studies, department of zoology, university of rajasthan, jaipur, india, India, reproductive physiology and biochemistry section, center for advanced studies, department of zoology, university of rajasthan, jaipur, india., India, reproductive physiology and biochemistry section, center for advanced studies, department of zoology, university of rajasthan, jaipur, india., India
پست الکترونیکی drmeera_agarwal@yahoo.co.in
 
     
   
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