adnexal mass with extremely high levels of ca-125 and ca19-9 but normal human epididymis protein 4 (he4) and risk of ovarian malignancy algorithm (roma): endometriosis or ovarian malignancy? a case report

Background: it has been shown that carbohydrate antigen (ca) 125 and ca 19-9 tumor markers are useful for diagnosis and follow up of ovarian carcinoma. case: in this case, we reported the high level of ca-125 and ca 19-9 with large right ovarian intact endometrioma and extensive involvement of omentum. conclusion: human epididymis protein (he4) and risk of ovarian malignancy algorithm (roma) can be useful in differentiation between malignancies and benign pathologies with a good sensitivity and specificity value.