Correlation between serum lipids profile with spermparameters of infertile men with abnormal semenanalysis

Background: one of the main laboratory tests for evaluation of infertility is semenanalysis (sa). however, additional tests may be suggested for further diagnosis of malefertility potentials. the seminal fluid contains sperms, non-sperm cells, and varioustypes of lipids and glucose.objective: the objective of this cross-sectional study was to correlate the spermparameters with concentrations of cholesterol, triglyceride, ldl, and hdl in serumsamples of infertile men with abnormal sa.materials and methods: a total of 120 infertile men (aged 23-49 years) with abnormalsa were enrolled for this cross-sectional study. sperm concentration and motility wasevaluated using makler chamber. while, normal morphology was done after geimsastaining. following 12 h of fasting, the blood samples were obtained for evaluation ofcholesterol, triglyceride, ldl, and hdl levels. the lipid profiles were compared withthe rates of normal and abnormal sperm parameters. chi-square and fisher exact testswere used for data evaluation.results: 75.5% and 98% of the subjects with normal levels of triglyceride had abnormalsperm morphology and progressive motility, respectively. also, abnormal levels oftriglyceride and cholesterol were related with abnormal sperm morphology and motility.the levels of ldl and hdl were normal in 80% and 89.3% of the cases, respectively.the majority of the patients with normal ldl had abnormal sperm parameters.conclusion: the results showed that the concentrations of serum lipids were notgenerally related with the quality of semen parameters. further studies on the role oflipid profiles of infertile men with sperm fertilizing potentials are necessary.