Creutzfeldt-Jacob Disease in an Iranian Patient Confirmed By Brain Autopsy

Creutzfeldt-jacob disease is the most common form of priondiseases, which have become public health problems in thelast two decades because of the high number of reported casesof mad cow disease in great britain and other countries.creutzfeldt-jacob disease is a fatal situation with known cardinalclinical features including progressive memory loss andmyoclonic seizure disorder. in this report, we present a case ofcreutzfeldt-jacob disease with characteristic clinical signssuch as progressive memory loss, myoclonic jerks, and focaland generalized seizures. we also discuss the pathologic findingsof the brain autopsy confirmed by gottingen center(germany) for spongiform encephalopathy.iran j med sci 2008; 33(2): 124-126.