Antireflux Valve in Post Cholecystojejunostomy Cholangitis: An Animal Study

Background: one of the most important post-operation problemsencountered with hepaticojejunostomy (kasai operation)in patients with biliary atresia is cholangitis. the aim of thisstudy was to evaluate the efficiency of anti-reflux valve in decreasingthe incidence of cholangitis after hepaticojejunostomy.methods: ten dogs were randomly divided into two groups ofequal size. in group a roux-en-y cholecystojejunostomy wasperformer and in group b antireflux valve was also added.three months later, liver biopsy was taken to evaluate histopatholicchanges.results: the incidence of cholangitis was significantly reducedin dogs in which anti-reflux valve procedure was performed.conclusions: anti-reflux valve procedure effectively decreasedpost-roux-en-y cholecystojejunostomy cholangitis indogs. therefore it is plausible and might be beneficial for patientsbeing treated for biliary atresia