Pyrexia in a Patient with Megaloblastic Anemia: A Case Report and Literature Review

Deficiency of vitamin b12 and/or folic acid as a cause of pyrexia, though known, is rarely reported in literature. we aimed to report a case in a 51 year old woman, who presented with fever and pancytopenia and was diagnosed to have megaloblastic anemia secondary to vitamin b12 a nd folate d eficiency. t he p yrexia subsided following the intramuscular injection of vitamin b12 and oral folic acid administration. all the other infective, inflammatory/autoimmune, endocrine causes of pyrexia were excluded by appropriate investigations. therefore, we suggest that all physicians be aware of megaloblastic anemia as a treatable cause of pyrexia in order to avoid unnecessary costly investigations and antibiotic usage.