Measles Sero-surveillance in Soldiers prior to Nation-wide Vaccination in Iran

Background: measles is a contagious respiratory viralinfection that accompanied with skin rash. vaccinationagainst measles has reduced the prevalence of the diseasebut sporadic measles epidemic still occurred in youngpeople. this study, was carried out for the responseevaluation of immunity against measles in iranian soldiersliving in garrisons.methods: in this study based on the history of measles, contactwith measles cases, measles in the family and vaccination,360 sera samples were obtained from male soldiers livingin tehran during years of 2003-2004 using elisamethod.results: whereas, 48.9% and 22.5% of cases were negativefor igg and igm respectively, 22.5% of the samples wereseronegative for both igg and igm isotypes. the respectiveantibody titers of igg and igm were 14.45% and 36.56%.regarding 22.5% negative cases for igg isotype and 36.67%of positive igm is indicative of possible latest outbreak.conclusion: single vaccination against measles during childhoodwas not protective and requires booster injections.