Amyotrophic Lateral Sclerosis in a Patient with Behcet's Disease

Beh cets d isease is a multisystem vasc ulit is. its neurologicalinvo lvement mostly includes par en chymal and nonparenchymal ce ntra l nervou s system manifestati ons. periphera l ner vou s system pre sentat ions a re rar e. a 32-yr-old malepatient who fulfill ed the internati on al study gro up criteria forbehc et ' s dis ea se, referred to our center with walking diffi cultyand repeated fallin g downs . ne uro logica l exa mination revealed weakn ess, wast ing and fasc iculation o f di stal musclesassociated wi th corticos pina l s igns . ne uro imaging data wereinsigni ficant but e lectrodiagnostic stu dies were in favor of motor neuron di sease. to bes t of our knowledge, thi s is the firstrep ort of assoc iation of amyot rophic later al sc leros is (al.s)and beh cets di sease.