Effects of Ocimum Basilicum on Functional Dyspepsia: a Double-Blind PlaceboControlled Study

Background: traditi onally some people employ ocimumbasilicuni (shas pram) to re lieve the symptoms of dy sp epsia.we therefore stud ied the effects of oral extract of thi s medicinalplant o n functi onal dy sp ep sia .methods: in a double-blind placebo-controll ed c linica l trial ,th e effect of a four-week tre atment of sh aspram was eva luated0 11 fun ctional dysp ep sia. two hundred cases from a ll pati ent sreferred for dysp epsia without hav ing any o bv ious pathologics igns were randoml y divid ed into case and co ntro l groups (100eac h) . the hydroalcoholic ex trac t of leaves of shaspram wasprepared and used . pat ient s were asked to hav e 30 drop s of prescribedmedi cations (placebo or the ex tract, equa l to 1.5 gramleaves powd er) dail y at 30 min befor e lunch and dinner forfour-weeks. severity was scored for eac h symptom on a numberedsca le and the res ults compared with th e results of placebogroup or pretr eatment period .results: pati ents in dru g gro up resp onded to treatment bett erthan pati ent s in placebo gro up ( p(less than)o.ooi). shasprarn was moreeffec tive in fem ale and yo ung patients. pati ents with fun ction aldyspepsia that had dysmotility problems a lso responded toshas pram better than others.conclusion: ocim um basilicum see ms to rei ieve th e sympto msof fun cti on al dysp epsia es pec ia lly in fema le and young patientswith dysm oti lity.