Cutaneous Manifestations of Systemic Lupus Erythematosus in Iranian Children

Systemic lupus erythematous (sle) is an autoimmune processin which cutaneous lesions occur in majority of patients. thisstudy was conducted to determine the pattern and prevalenceof such lesions in sle in iranian children infected with sle.forty-eight patients, age between 3-16 yrs and male to femaleratio of 7/1 were examined for the presence of cutaneousmanifestations of sle. the most common skin changes notedwere malar rash, discoid eruptions, alopecia, and photosensitivity.vascular lesions including peripheral gangrene, chroniculcers, raynauds phenomenon, urticaria, palmar erythema,and erythema multiform were rare. anti nuclear antibodiesand anti-ds-dna were positive. the prominent part of sle isskin change which may be used as helpful diagnostic means.the result of the present study indicated that cutaneous involvementswere more common in iranian children and thesechanges would provide helpful information in early diagnosisofjuvenile systemic lupus erythematous