Total IgE Levels in Healthy Children in Tehran, Iran

Determining the normal range of immunoglobulin e (lge) inany population is important for diagnosis of allergic diseases.the aim of this study was to determine normal values of 19ein children living in tehran. two-handed and fifty sixhealthy children aged one month to 14 years were selected.these children had neither parasitic infections nor atopic disease.they were divided into six groups and the total serumige levels were measured by eusa methods. the referencesrange of the ige levels were 0.1-25, 0.8-162, 0.6-184,3-221,2.9-501 and 2-316 ku/l in age groups as follows: (less than)3month, 4-12 months, 1-3, 3-7, 7-10, and 10-14 years respectively.ige levels were higher in boys but were not statisticallysignificant except in 4-12-month olds (p(less than)0.005). therewas also an increase in ige levels with age. normal value ofserum total ige obtained in this study could be useful to contributefor diagnosis of allergic disease, as reference rangesin iranian healthy children.