Antitussive Effect of Plantago lanceolata in Guinea Pigs

Background: several therapeutic effects including antiasthmaand dyspnea have been described for plantago lanceolata.in the present study the antitussive effect of this plantwas evaluated.methods: the antitussive effects of aerosols of two differentconcentrations of soxhlet and macerated ethanolic extracts,codeine and saline were tested by counting the number ofcoughs produced due to aerosol of citric acid 10 min after exposingthe animal to aerosols of different solutions (n=8 foreach solution).results: the results showed significant reductions of coughnumber observed in the presence of both concentrations of soxhletand macerated extracts of plantago lanceolata as comparedto saline treated group (p(less than)o.ool). the reduced cough numberobserved in the presence of higher concentrations of extractswas not significantly different from that of lower concentrationsoflp. furthermore, there was no significant difference betweenthe cough numbers observed in the presence of both concentrationsof the extracts with that of codeine.conclusion: the ethanolic extracts of plantago lanceolatahave antitussive effects comparable with that of codeine