quality of life assessment in patients with behçet’s disease using the persian version of the leeds bd-qol questionnaire

Background: behçet’s disease (bd) can negatively impact the quality of life (qol) of the affected patients. the present study aimed to assess the qol of bd patients using the leeds bdqol and compare its results with the whoqolbref questionnaire. methods: in the present cross-sectional study, 179 bd patients and 304 healthy individuals (the control group) were recruited in shiraz, 2017. the persian version of the leeds bdqol and whoqolbref questionnaires were used to assess the qol of patients with bd. the qol in the patient and control groups was compared after controlling the effect of some variables (age, sex, marital status, and educational level) using the multiple linear regression analysis. spearman’s correlation coefficient was calculated for the leeds bdqol and whoqolbref scores. disease activity was measured using the behçet’s disease current activity form. all the statistical analysis was performed using spss software (version 21.0). p results: the mean of the leeds bdqol total score in the patient group was 12.3±8.7. the control group had significantly higher scores in the whoqolbref total score and the physical health and psychological health domains compared with the patient group; mean difference of 10.24, 10.8, and 4.62, respectively (p =0.001). the spearman’s correlation coefficient for the leeds bdqol score and whoqolbref total score and its domains (physical health, psychological health, social relationships, and environment) was 0.669, 0.713, 0.714, 0.536, and 0.550, respectively. the disease activity score was correlated with the leeds bdqol score (r=0.361, p =0.001). conclusion: bd patients had a lower qol than healthy individuals, specifically in the physical health and psychological health domains. an increase in disease activity and severity was associated with a reduced qol. the persian version of the leeds bdqol questionnaire had an acceptable correlation with the whoqolbref questionnaire.