Effect of Surface Modification on Viability of L929 Cells on Zirconia Nanocomposite Substrat

Introduction: zirconia bioceramic can be considered for metallic replacement in dental implant applications. a proper method of surface modification may promote better osseointegration. methods: in study evaluated viability of fibroblast cell following surface treatment. therefore, viability l929 cells were characterized using mtt assay and scanning electron microscopy. results: the viability assessment determined significant differences a-y-tzp20 without surface treatment as compared to laser surface treatment (b), laser surface treatment + hydroxyapatite- yttrium stabilized tetragonal zirconia nanocomposite coat (c) and control. this study demonstrated that l929 cells approximately proliferated and spread on a-y-tzp20 nanocomposite disk in laser surface treatment(b), laser surface treatment + hydroxiapatite-yttrium stabilized tetragonal zirconia nanocomposite coat (c) groups similar to control group. conclusion: laser surface treatment showed positive effect on the viability of l929 cells.